diff --git a/src/main.cpp b/src/main.cpp
index 17867c869..c80a4ac92 100644
--- a/src/main.cpp
+++ b/src/main.cpp
@@ -2345,6 +2345,7 @@ bool ConnectBlock(const CBlock& block, CValidationState& state, CBlockIndex* pin
 
     CCheckQueueControl<CScriptCheck> control(fScriptChecks && nScriptCheckThreads ? &scriptcheckqueue : NULL);
 
+    std::vector<uint256> vOrphanErase;
     std::vector<int> prevheights;
     CAmount nFees = 0;
     int nInputs = 0;
@@ -2377,6 +2378,17 @@ bool ConnectBlock(const CBlock& block, CValidationState& state, CBlockIndex* pin
                 prevheights[j] = view.AccessCoins(tx.vin[j].prevout.hash)->nHeight;
             }
 
+            // Which orphan pool entries must we evict?
+            for (size_t j = 0; j < tx.vin.size(); j++) {
+                auto itByPrev = mapOrphanTransactionsByPrev.find(tx.vin[j].prevout);
+                if (itByPrev == mapOrphanTransactionsByPrev.end()) continue;
+                for (auto mi = itByPrev->second.begin(); mi != itByPrev->second.end(); ++mi) {
+                    const CTransaction& orphanTx = (*mi)->second.tx;
+                    const uint256& orphanHash = orphanTx.GetHash();
+                    vOrphanErase.push_back(orphanHash);
+                }
+            }
+
             if (!SequenceLocks(tx, nLockTimeFlags, &prevheights, *pindex)) {
                 return state.DoS(100, error("%s: contains a non-BIP68-final transaction", __func__),
                                  REJECT_INVALID, "bad-txns-nonfinal");
@@ -2464,6 +2476,15 @@ bool ConnectBlock(const CBlock& block, CValidationState& state, CBlockIndex* pin
     GetMainSignals().UpdatedTransaction(hashPrevBestCoinBase);
     hashPrevBestCoinBase = block.vtx[0].GetHash();
 
+    // Erase orphan transactions include or precluded by this block
+    if (vOrphanErase.size()) {
+        int nErased = 0;
+        BOOST_FOREACH(uint256 &orphanHash, vOrphanErase) {
+            nErased += EraseOrphanTx(orphanHash);
+        }
+        LogPrint("mempool", "Erased %d orphan tx included or conflicted by block\n", nErased);
+    }
+
     int64_t nTime6 = GetTimeMicros(); nTimeCallbacks += nTime6 - nTime5;
     LogPrint("bench", "    - Callbacks: %.2fms [%.2fs]\n", 0.001 * (nTime6 - nTime5), nTimeCallbacks * 0.000001);