diff --git a/src/base/preferences.cpp b/src/base/preferences.cpp
index 1af6cd76a..180c40dd4 100644
--- a/src/base/preferences.cpp
+++ b/src/base/preferences.cpp
@@ -55,9 +55,20 @@
 
 #include "algorithm.h"
 #include "global.h"
+#include "profile.h"
 #include "settingsstorage.h"
 #include "utils/fs.h"
 
+namespace
+{
+    QString makeProfileID(const QString &profilePath, const QString &profileName)
+    {
+        return profilePath.isEmpty()
+                ? profileName
+                : profileName + QLatin1Char('@') + Utils::Fs::toValidFileSystemName(profilePath, false, {});
+    }
+}
+
 Preferences *Preferences::m_instance = nullptr;
 
 Preferences::Preferences() = default;
@@ -310,21 +321,31 @@ void Preferences::setPreventFromSuspendWhenSeeding(const bool b)
 #ifdef Q_OS_WIN
 bool Preferences::WinStartup() const
 {
-    QSettings settings("HKEY_CURRENT_USER\\Software\\Microsoft\\Windows\\CurrentVersion\\Run", QSettings::NativeFormat);
-    return settings.contains("qBittorrent");
+    const QString profileName = Profile::instance()->profileName();
+    const QString profilePath = Profile::instance()->rootPath();
+    const QString profileID = makeProfileID(profilePath, profileName);
+    const QSettings settings {"HKEY_CURRENT_USER\\Software\\Microsoft\\Windows\\CurrentVersion\\Run", QSettings::NativeFormat};
+
+    return settings.contains(profileID);
 }
 
 void Preferences::setWinStartup(const bool b)
 {
-    QSettings settings("HKEY_CURRENT_USER\\Software\\Microsoft\\Windows\\CurrentVersion\\Run", QSettings::NativeFormat);
+    const QString profileName = Profile::instance()->profileName();
+    const QString profilePath = Profile::instance()->rootPath();
+    const QString profileID = makeProfileID(profilePath, profileName);
+    QSettings settings {"HKEY_CURRENT_USER\\Software\\Microsoft\\Windows\\CurrentVersion\\Run", QSettings::NativeFormat};
     if (b)
     {
-        const QString binPath = '"' + Utils::Fs::toNativePath(qApp->applicationFilePath()) + '"';
-        settings.setValue("qBittorrent", binPath);
+        const QString configuration = Profile::instance()->configurationName();
+
+        const auto cmd = QString::fromLatin1(R"("%1" "--profile=%2" "--configuration=%3")")
+                .arg(Utils::Fs::toNativePath(qApp->applicationFilePath()), profilePath, configuration);
+        settings.setValue(profileID, cmd);
     }
     else
     {
-        settings.remove("qBittorrent");
+        settings.remove(profileID);
     }
 }
 #endif // Q_OS_WIN